It’s been said many times that men just don’t understand women.

Now, we have SCIENCE! to back that up.

According to a study performed by the Indiana University’s Department of Psychological and Brain Sciences, us gentlemen just have ZERO idea what exactly you ladies are up to…

More often than not, guys interpret even friendly cues, such as a subtle smile from a gal, as a sexual come-on, and a new study discovers why: Guys are clueless.

More precisely, they are somewhat oblivious to the emotional subtleties of non-verbal cues, according to a new study of college students.

“Young men just find it difficult to tell the difference between women who are being friendly and women who are interested in something more,” said lead researcher Coreen Farris of Indiana University’s Department of Psychological and Brain Sciences.

This “lost in translation” phenomenon plays out in the real world, with about 70 percent of college women reporting an experience in which a guy mistook her friendliness for a sexual come-on, Farris said.

Some might think the results come down to “boys being boys,” and so even the slightest female interest sparks sexual fantasy. But the study, to be detailed in the April issue of the journal Psychological Science, also found that it goes both ways for guys — they mistake females' sexual signals as friendly ones. The researchers suggest guys have trouble noticing and interpreting the subtleties of non-verbal cues, in either direction.